An internal standard for the quantification of sphingosine (d18:1) by GC- or LC-MS

Sphingosine-d7 (d18:1) – 1 mg

Brand:
Cayman
CAS:
1246304-34-6
Storage:
-20
UN-No:
Non-Hazardous - /

Sphingosine-d7 (d18:1) is intended for use as an internal standard for the quantification of sphingosine (d18:1) (Item No. 10007907) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.{13592} Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.{13592} Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.{11895,12477,10628}  

 

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Description

An internal standard for the quantification of sphingosine (d18:1) by GC- or LC-MS

Formal name: (2S,3R,4E)-2-amino-4-octadecene-16,16,17,17,18,18,18-d7-1,3-diol

Synonyms:  (−)-Sphingosine-d7|D-erythro-Sphingosine C-18-d7

Molecular weight: 306.5

CAS: 1246304-34-6

Purity: ≥99% deuterated forms (d1-d7)

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cell Biology|Cell Signaling||Research Area|Lipid Biochemistry|Sphingolipids

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