A fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities; scavenges DPPH radicals (IC50 = 5 mM); prevents PAF-induced PARP cleavage in PC12-AC cells and PAF-induced cytotoxicity in Pafr-/-mouse cerebellar granule cells at 1 μg/ml

Orsellinic Acid – 10 mg

Brand:
Cayman
CAS:
480-64-8
Storage:
-20
UN-No:
Non-Hazardous - /

Orsellinic acid is a fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities.{43371,43459} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals with an IC50 value of 5 mM.{43371} Orsellinic acid (1 μg/ml) prevents PARP cleavage induced by platelet-activating factor (PAF) in PC12-AC cells and PAF-induced cytotoxicity in PAF receptor null (Pafr-/-) mouse cerebellar granule cells.{43459}  

 

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Description

A fungal metabolite and benzoic acid derivative with antioxidant and neuroprotective activities; scavenges DPPH radicals (IC50 = 5 mM); prevents PAF-induced PARP cleavage in PC12-AC cells and PAF-induced cytotoxicity in Pafr-/-mouse cerebellar granule cells at 1 μg/ml

Formal name: 2,4-dihydroxy-6-methyl-benzoic acid

Synonyms: 

Molecular weight: 168.2

CAS: 480-64-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Neuroscience|Neuroprotection||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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