Description
A peptide activator of PI3K; binds to the p85 N- and C-terminal SH2 domains of PI3K in an affinity purification assay; cell-permeable and stimulates mitogenesis in serum-starved C2 cells at a concentration of 50 μg/ml; reverses inhibition of PI3K by schisandrin B in U251 and U87 melanoma cells, inducing expression of p-mTOR and MMP-9
Formal name: L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysyl-L-seryl-L-α-aspartylglycylglycyl-O-phosphono-L-tyrosyl-L-methionyl-L-α-aspartyl-L-methionyl-L-serine
Synonyms:
Molecular weight: 3,270.70
CAS: 1236188-16-1
Purity: ≥85%
Formulation: A crystalline solid
Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cancer|Cell Signaling|PI3K/Akt/mTOR Signaling||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Cell Signaling|PI3K/Akt/mTOR Signaling
