Stachybotrylactam – 2.5 mg

Brand:
Cayman
CAS:
163391-76-2
Storage:
-20
UN-No:
Non-Hazardous - /

Stachybotrylactam is a spirodihydrobenzofuranlactam mycotoxin originally isolated from Stachybotrys with antiviral activity.{39040,39041} It inhibits HIV-1 protease in vitro with an IC50 value of 161 μM.{39041} Stachybotrylactam has no effect on oleic acid-elicited intracellular lipid accumulation and has no observable cytotoxicity at concentrations up to 100 μM in HepG2 cells.{39042}  

 

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SKU: 22584 - Category:

Description

A mycotoxin with antiviral activity; it inhibits HIV-1 protease in vitro (IC50 = 161 μM); no observable cytotoxicity at concentrations up to 100 μM in HepG2 cells,


Formal name: (1’R,2’R,4’aS,6’R,8’aS)-3′,4′,4’a,5′,6′,7,7′,8,8′,8’a-decahydro-4,6′-dihydroxy-2′,5′,5′,8’a-tetramethyl-spiro[2H-furo[2,3-e]isoindole-2,1′(2’H)-naphthalen]-6(3H)-one

Synonyms: 

Molecular weight: 385.5

CAS: 163391-76-2

Purity: ≥95%

Formulation: A lyophilisate


Product Type|Biochemicals|Antivirals|Protease Inhibitors||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS