A bioactive sphingolipid; inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells (IC50s = 44.1 and 46 μM

C10 Ceramide (d18:1/10:0) – 10 mg

Brand:
Cayman
CAS:
111122-57-7
Storage:
-20
UN-No:
Non-Hazardous - /

C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase.{38331} C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 μM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent manner. [Matreya, LLC. Catalog No. 1333]  

 

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Description

A bioactive sphingolipid; inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells (IC50s = 44.1 and 46 μM, respectively); inhibits the growth of J774 murine macrophages in a dose-dependent manner,

Formal name: N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-decanamide

Synonyms:  C10 Ceramide|Cer(d18:1/10:0)|Ceramide (d18:1/10:0)|N-decanoyl-D-erythro-Sphingosine

Molecular weight: 453.7

CAS: 111122-57-7

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cancer|Multidrug Resistance||Research Area|Lipid Biochemistry|Sphingolipids

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