A pteridine that inhibits ENaC

Triamterene – 1 mg

Brand:
Cayman
CAS:
396-01-0
Storage:
-20
UN-No:
Non-Hazardous - /

Triamterene (Item No. 22486) is an analytical reference standard that is categorized as a pteridine. Triamterene is an inhibitor of the epithelial sodium channel (ENaC) that increases renal sodium excretion and decreases potassium excretion. It inhibits rat ENaC with an IC50 value of 4.5 µM.{33172} Diuretics, including triamterene, have been abused as performance-enhancing drugs and masking agents in sports doping.{33139} This product is intended for research and forensic applications.  

 

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Description

A pteridine that inhibits ENaC, increases renal sodium excretion, and decreases potassium excretion; has been abused as a performance-enhancing drug and masking agent in sports doping,

Formal name: 6-phenyl-2,4,7-pteridinetriamine

Synonyms:  NSC 77625|SKF 8542

Molecular weight: 253.3

CAS: 396-01-0

Purity: ≥98%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Performance-Enhancing Drugs|Diuretics

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