An impurity found in the preparation of BAR501; GP-BAR1 agonist; induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay at a concentration of 10 µM

BAR501 Impurity – 1 mg

Brand:
Cayman
CAS:
1632118-70-7
Storage:
-20
UN-No:
Non-Hazardous - /

BAR501 impurity is an impurity found in the preparation of BAR501 (Item No. 22460) that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1). BAR501 impurity (10 µM) induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay.{35043}  

 

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Description

An impurity found in the preparation of BAR501; GP-BAR1 agonist; induces a 150% increase in luciferase activity in a GP-BAR1 reporter gene assay at a concentration of 10 µM,

Formal name: (3α,5β,6β,7α)-6-ethyl-cholane-3,7,24-triol

Synonyms: 

Molecular weight: 406.6

CAS: 1632118-70-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Pharmaceutical Impurities||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Vasculature|Vasodilation||Research Area|Endocrinology & Metabolism|Bile Acids & Microbiome||Research Area|Immunology & Inflammation|Gastric Disease|Crohn’s Disease||Research Area|Immunology & Inflammation|Innate Immunity

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