Description
A xanthone glucoside with diverse biological activities; increases survival of HIV-1-infected MT-2 human leukemia cells (EC50 = 3.59 μg/ml); inhibits tumor growth and increases lifespan in an AFS mouse xenograft model at 10 μg/g; reduces TPA-induced production of H2O2 by mouse peritoneal macrophages ex vivo at 50 mg/kg; decreases TPA-induced DNA fragmentation in mouse liver and brain at 50 mg/kg; increases survival of γ-irradiated mice from 0.25-2 mg/kg; reduces fasting plasma glucose, total cholesterol, triglycerides, and LDL-C levels in a rat model of streptozotocin-induced diabetes by 50, 57, 38.5, and 70%, respectively, at 10 mg/kg, i.p.
Formal name: 2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
Synonyms: NSC 248870
Molecular weight: 422.3
CAS: 4773-96-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|DNA Damage and Repair||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen
