A potent inhibitor of pancreatic elastase (Ki = 240 nM); more strongly inhibits pancreatic elastase versus the leukocyte derived enzyme; reduces electrophoretic mobilities of 2A proteinases from poliovirus and human rhinovirus 14 in a dose-dependent manner; inhibits elastase-like protease collagenolytic protease from C. maenas digestive glands

Elastatinal – 5 mg

Brand:
Cayman
CAS:
51798-45-9
Storage:
-20
UN-No:
Non-Hazardous - /

Elastatinal is a potent inhibitor of pancreatic elastase (Ki = 240 nM) that is produced by various species of Actinomycetes.{39141} It more strongly inhibits pancreatic elastase versus the leukocyte-derived enzyme.{39142,39143} Elastatinal reduces electrophoretic mobilities of 2A proteinases from poliovirus and human rhinovirus 14 in a dose-dependent manner, indicating substrate recognition by 2A proteinases is similar to that of pancreatic elastases.{39144} It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands.{39145}  

 

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Description

A potent inhibitor of pancreatic elastase (Ki = 240 nM); more strongly inhibits pancreatic elastase versus the leukocyte derived enzyme; reduces electrophoretic mobilities of 2A proteinases from poliovirus and human rhinovirus 14 in a dose-dependent manner; inhibits elastase-like protease collagenolytic protease from C. maenas digestive glands,

Formal name: (2S)-2-[(4S)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxyethyl]-L-glutamamide

Synonyms: 

Molecular weight: 512.6

CAS: 51798-45-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases

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