An internal standard for the quantification of L-DOPA by GC- or LC-MS

L-DOPA-d3 – 250 mg

Brand:
Cayman
CAS:
53587-29-4
Storage:
-20
UN-No:
Non-Hazardous - /

L-DOPA-d3 is intended for use as an internal standard for the quantification of L-DOPA (Item No. 13248) by GC- or LC-MS. L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood-brain barrier.{17819} It is produced from L-tyrosine by tyrosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. Formulations containing L-DOPA have been used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery.  

 

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Description

An internal standard for the quantification of L-DOPA by GC- or LC-MS

Formal name: 5-hydroxy-L-tyrosine-2,3,6-d3

Synonyms:  3,4-Dihydroxyphenylalanine-d3|Levodopa-d3

Molecular weight: 200.2

CAS: 53587-29-4

Purity: ≥99% deuterated forms (d1-d3)

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Neurodegenerative Disorders|Parkinson’s Disease

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