A macrolide antibiotic; a semi-synthetic erythromycin derivative; improved pH stability and absorption over erythromycin; prevents protein synthesis; binds ribosome polypeptide exit tunnel

Lexithromycin – 5 mg

Brand:
Cayman
CAS:
53066-26-5
Storage:
-20
UN-No:
Non-Hazardous - /

Lexithromycin is a semi-synthetic antibiotic derived from erythromycin (Item No. 16486).{39024} Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability.{39024} As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel.{22680} Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.  

 

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Description

A macrolide antibiotic; a semi-synthetic erythromycin derivative; improved pH stability and absorption over erythromycin; prevents protein synthesis; binds ribosome polypeptide exit tunnel,

Formal name: erythromycin, 9-(O-methyloxime)

Synonyms: 

Molecular weight: 763

CAS: 53066-26-5

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Macrolides||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS

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