A proton pump inhibitor and pure enantiomer of lansoprazole; inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 µM); inhibits acid formation in isolated canine parietal cells (IC50 = 82 µM)

(S)-Lansoprazole – 10 mg

Brand:
Cayman
CAS:
138530-95-7
Storage:
-20
UN-No:
Non-Hazardous - /

(S)-Lansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 µM), inhibiting gastric acid secretion and increasing intragastric pH.{18250} It also inhibits acid formation in isolated canine parietal cells (IC50 = 82 µM). (S)-Lansoprazole is an enantiomerically pure form of lansoprazole (Item No. 13627). Both (S)- and (R)-lansoprazole (Item No. 18235) are pharmacologically active with similar potencies.{18250}  

 

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Description

A proton pump inhibitor and pure enantiomer of lansoprazole; inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 µM); inhibits acid formation in isolated canine parietal cells (IC50 = 82 µM)

Formal name: 2-[(S)-[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole

Synonyms:  (-)-Lansoprazole

Molecular weight: 369.4

CAS: 138530-95-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|ATPases||Research Area

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