An inhibitor of PRMT1 (IC50 = 11 μM in a histone H4 methylation assay); inhibits histone H4 methylation by PRMT8

CID-2818500 – 5 mg

Brand:
Cayman
CAS:
1215-07-2
Storage:
-20
UN-No:
Non-Hazardous - /

CID-2818500 is an inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50 = 11 μM in a histone H4 methylation assay).{47652} It also inhibits histone H4 methylation by PRMT8, but not histone H3.1 methylation by CARM1 or Set7/9, when used at concentrations of 10 and 100 μM.  

 

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Description

An inhibitor of PRMT1 (IC50 = 11 μM in a histone H4 methylation assay); inhibits histone H4 methylation by PRMT8, but not histone H3.1 methylation by CARM1 or Set7/9, at 10 and 100 μM

Formal name: 1,1′-(1-nitro-1,2-ethenediyl)bis-benzene

Synonyms:  NSC 385|α-Nitrostilbene

Molecular weight: 225.2

CAS: 1215-07-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Methyltransferases||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Methylation

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