An ω-7 monounsaturated fatty acid; increases basal and insulin-stimulated glucose uptake and Glut4 protein levels in 3T3-L1 adipocytes at 200 µM; ex vivo

Palmitoleic Acid (sodium salt) – 5 g

Brand:
Cayman
CAS:
6610-24-8
Storage:
-20
UN-No:
Non-Hazardous - /

Palmitoleic acid is an ω-7 monounsaturated fatty acid that has been found in macadamia and sea buckthorn oils.{14132,14133} It increases basal and insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) protein levels in 3T3-L1 adipocytes when used at a concentration of 200 µM.{52425} Ex vivo, palmitoleic acid (300 mg/kg per day) increases glucose uptake and aerobic and anaerobic glycolysis and reduces de novo fatty acid synthesis and activity of the lipogenic enzymes ATP citrate lyase (ACL) and glucose-6-phosphate dehydrogenase (G6PDH) in isolated murine adipocytes. Dietary administration of palmitoleic acid (300 mg/kg) reduces high-fat diet-induced insulin resistance and liver inflammation in mice.{52426}  

 

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Description

An ω-7 monounsaturated fatty acid; increases basal and insulin-stimulated glucose uptake and Glut4 protein levels in 3T3-L1 adipocytes at 200 µM; ex vivo, increases glucose uptake and aerobic and anaerobic glycolysis and reduces de novo fatty acid synthesis and activity of the lipogenic enzymes ACL and G6PDH in isolated murine adipocytes at 300 mg/kg; dietary administration reduces high-fat diet-induced insulin resistance and liver inflammation in mice at 300 mg/kg

Formal name: 9Z-hexadecenoic acid, monosodium salt

Synonyms:  (9Z)-Hexadecenoic Acid|cis-Palmitoleic Acid|C16:1 n-7|C16:1(9Z)

Molecular weight: 276.4

CAS: 6610-24-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Fatty Acids||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Endocrinology & Metabolism|Carbohydrate Metabolism||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Fatty Acids

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