A xanthine derivative that antagonizes adenosine receptors (Kis = 44

3-Propylxanthine – 50 mg

Brand:
Cayman
CAS:
41078-02-8
Storage:
-20
UN-No:
Non-Hazardous - /

3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 µM for A1, A2A, and A2B, respectively) and cAMP phosphodiesterase (Ki = 42 µM).{27926,33858,29142} Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.{33856,33857,33858}  

 

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Description

A xanthine derivative that antagonizes adenosine receptors (Kis = 44, 32, and 6.3 µM for A1, A2A, and A2B, respectively) and cAMP PDE(Ki = 42 µM); induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness

Formal name: 3,9-dihydro-3-propyl-1H-purine-2,6-dione

Synonyms:  D 4028|Enprofylline

Molecular weight: 194.2

CAS: 41078-02-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Small Molecule Inhibitors|Phosphodiesterases||Research Area|Immunology & Inflammation|Allergy

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