A lichen metabolite with diverse biological activities; active against various bacteria (MICs = 4-16 μg/ml); prevents UVB-induced apoptosis

Vulpinic Acid – 10 mg

Brand:
Cayman
CAS:
521-52-8
Storage:
-20
UN-No:
Non-Hazardous - /

Vulpinic acid is a lichen metabolite that has been found in L. vulpina and has diverse biological activities.{50292,50293,50294,50295} It is active against C. perfringens, B. vulgatus, B. fragilis, B. loescheii, P. acnes, E. faecium, and methicillin-susceptible and -resistant S. aureus (MICs = 4-16 μg/ml).{50292} Vulpinic acid (25-800 μM) prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes.{50293} It also increases scratch wound healing of HaCaT cells.{50294} Vulpinic acid (15 μM) reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and cytotoxicity in human umbilical vein endothelial cells (HUVECs).{50295}  

 

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Description

A lichen metabolite with diverse biological activities; active against various bacteria (MICs = 4-16 μg/ml); prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes from 25-800 μM; increases scratch wound healing of HaCaT cells; reduces hydrogen peroxide-induced production of ROS and cytotoxicity in HUVECs at 15 μM

Formal name: αE-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-benzeneacetic acid, methyl ester

Synonyms:  NSC 5897

Molecular weight: 322.3

CAS: 521-52-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cell Biology|Cytoskeleton & Motor Proteins||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Food-borne Illnesses||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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