A nitrofuran antibiotic; active against laboratory strains of S. aureus

Nitrofurazone – 100 g

Brand:
Cayman
CAS:
59-87-0
Storage:
-20
UN-No:
Non-Hazardous - /

Nitrofurazone is a nitrofuran antibiotic that is active against a variety of Gram-negative and Gram-positive bacteria including laboratory strains of S. aureus, E. faecalis, and E. coli (MICs = 8 μg/ml for all) as well as clinical isolates of several urinary tract pathogens including Enterococcus, coagulase-negative staphylococci, Klebsiella, and P. mirabilis (MICs = 2-64 μg/ml).{37741,37742} Nitrofurazone induces mutagenicity in mammalian and bacterial cell-based assays and carcinogenesis, reproductive effects, and toxicity in rats and mice (LD50s = 590 and 640 mg/kg, respectively).{37743} Formulations containing nitrofurazone have been used in the topical treatment and prevention of bacterial infections in humans and animals as well as oral treatment of trypanosomiasis.  

 

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Description

A nitrofuran antibiotic; active against laboratory strains of S. aureus, E. faecalis, and E. coli (MICs = 8 μg/ml for all) as well as clinical isolates of several urinary tract pathogens including Enterococcus, coagulase-negative staphylococci, Klebsiella, and P. mirabilis (MICs = 2-64 μg/ml); induces mutagenicity in mammalian and bacterial cell-based assays and carcinogenesis, reproductive effects, and toxicity in rats and mice (LD50s = 590 and 640 mg/kg, respectively)

Formal name: 2-[(5-nitro-2-furanyl)methylene]-hydrazinecarboxamide

Synonyms:  Furacilin|Nitrofural|NSC 1602|NSC 2100|NSC 44009

Molecular weight: 198.1

CAS: 59-87-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Nitrofurans||Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Parasitic Diseases

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