A KLF5 inhibitor (IC50 = 2.3 μM); decreases KLF5 expression in and reduces growth of DLD-1 colorectal adenocarcinoma cells in a concentration-dependent manner; selectively inhibits proliferation of cancer cell lines that highly express KLF5 in the NCI-60 panel of cancer cell lines

CID-5951923 – 10 mg

Brand:
Cayman
CAS:
749872-43-3
Storage:
-20
UN-No:
Non-Hazardous - /

CID-5951923 is an inhibitor of the transcription factor Krüppel-like factor 5 (KLF5; IC50 = 2.3 μM).{35317} It decreases KLF5 expression in and reduces growth of DLD-1 colorectal adenocarcinoma cells in a concentration-dependent manner. CID-5951923 selectively inhibits proliferation of cancer cell lines that highly express KLF5, particularly colon adenocarcinomas, in the NCI-60 panel of cancer cell lines.  

 

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Description

A KLF5 inhibitor (IC50 = 2.3 μM); decreases KLF5 expression in and reduces growth of DLD-1 colorectal adenocarcinoma cells in a concentration-dependent manner; selectively inhibits proliferation of cancer cell lines that highly express KLF5 in the NCI-60 panel of cancer cell lines

Formal name: 3-(3-nitrophenyl)-2-propenoic acid, 2-[methyl(tetrahydro-1,1-dioxido-3-thienyl)amino]-2-oxoethyl ester

Synonyms: 

Molecular weight: 382.4

CAS: 749872-43-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Transcription Factors

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