Description
A β-carboline alkaloid with diverse activities; inhibits GSK3β and CDK5 (IC50s = 10.2 and 1.5 μM, respectively); inhibits the growth of L5178y mouse lymphoma cells (ED50 = 1.8 μg/mL); inhibits the growth of B. subtilis and S. aureus; reduces RT activity in supernatant from human PBMCs infected with HIV-1 (EC50 = 4.2 μM); reduces the amount of P. berghei in infected mice by over 90% relative to the control at 100 μmol/kg, i.p.; inhibits the growth of S. littoralis larva by 80% when added to the diet at 132 ppm,
Formal name: (1R,4S,9Z,13S,13aR,20aR,21aR)-2,3,5,6,7,8,11,12,15,16,17,18,20a,21-tetradecahydro-24-(9H-pyrido[3,4-b]indol-1-yl)-1,13-etheno-4,21a-methano-1H-azocino[1′,2′:1,5]pyrrolo[3,2-e]azacyclopentadecin-13(13aH)-ol
Synonyms: Keramamine A
Molecular weight: 548.8
CAS: 104196-68-1
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Kinase Inhibitors|CDKs||Product Type|Biochemicals|Kinase Inhibitors|GSK3||Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Pesticides|Insecticides||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Parasitic Diseases|Malaria||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Neuroscience
