A derivative of thymidine (Item No. 20519) that exhibits antiviral and anticancer activity by inhibiting thymidylate synthase

Trifluorothymidine – 500 mg

Brand:
Cayman
CAS:
70-00-8
Storage:
-20
UN-No:
Non-Hazardous - /

Trifluorothymidine is a derivative of thymidine that exhibits antiviral and anticancer activity by inhibiting thymidylate synthase, thereby blocking nucleic acid synthesis, and by incorporating into DNA, which leads to DNA damage and apoptosis.{33580}  

 

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Description

A derivative of thymidine (Item No. 20519) that exhibits antiviral and anticancer activity by inhibiting thymidylate synthase, thereby blocking nucleic acid synthesis, and by incorporating into DNA, which leads to DNA damage and apoptosis

Formal name: α,α,α-trifluoro-thymidine

Synonyms:  NSC 529182|NSC 75520|TFT|Trifluridine

Molecular weight: 296.2

CAS: 70-00-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|DNA Damage and Repair||Research Area|Infectious Disease|Viral Diseases

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