Description
A serotonin receptor antagonist active at 5-HT1 (pKi = 7.8 for 5-HT1B), 5-HT2, (pKi = 8.64, 8.75, and 8.75 for 5-HT2A, 5-HT2B, and 5-HT2C respectively), and 5-HT7 receptors; blocks 5-HT7 receptor-stimulated cAMP production (IC50 = 321 nM); dose-dependently inhibits voltage-dependent sodium and potassium channels
Formal name: N-[[(8β)-1,6-dimethylergolin-8-yl]methyl]-carbamic acid, phenylmethyl ester
Synonyms:
Molecular weight: 403.5
CAS: 17692-51-2
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety||Research Area|Neuroscience|Behavioral Neuroscience|Depression||Research Area|Neuroscience|Neuroendocrinology