A small molecule inhibitor activated coagulation factor VIIa with antithrombotic effects; exhibits antitumor activities

PCI 27483 – 5 mg

Brand:
Cayman
CAS:
871266-63-6
Storage:
-20
UN-No:
Non-Hazardous - /

PCI 27483 is a small molecule inhibitor of activated coagulation factor VIIa with antithrombotic effects in a baboon model of arterial thrombosis.{33500} It also inhibits the growth of BxPC3 xenografts by 42 and 85% at doses of 60 and 90 mg/kg, respectively.{33499}  

 

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Description

A small molecule inhibitor activated coagulation factor VIIa with antithrombotic effects; exhibits antitumor activities

Formal name: N-[2-[5-[6-(aminoiminomethyl)-1H-benzimidazol-2-yl]-5′-(aminosulfonyl)-2′,6-dihydroxy[1,1′-biphenyl]-3-yl]acetyl]-L-aspartic acid

Synonyms: 

Molecular weight: 596.6

CAS: 871266-63-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cancer||Research Area|Cardiovascular System|Blood|Acute Phase Reactants||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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