A potent

FLT3 Inhibitor III – 1 mg

Brand:
Cayman
CAS:
852045-46-6
Storage:
-20
UN-No:
Non-Hazardous - /

FLT3 Inhibitor III is a potent inhibitor of Fms-like tyrosine kinase 3 (FLT3; IC50 = 50 nM).{33905} It shows high selectivity for FLT3 over a panel of 300 other kinases.{33905,28555} FLT3 Inhibitor III blocks FLT-dependent cell proliferation in a dose-dependent manner.{33905} FLT3 Inhibitor III has been used to study signaling through FLT3 and FLT3 with internal tandem duplications (FLT3-ITD) in cells.{33904,33906,33907}  

 

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Description

A potent, highly selective inhibitor of FLT3 (IC50 = 50 nM); used to study signaling through FLT3 and FLT3-ITD in cells

Formal name: 5-phenyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-thiazolamine

Synonyms:  Fms-like Tyrosine Kinase Inhibitor III

Molecular weight: 365.5

CAS: 852045-46-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PDGFR Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|Growth Factor Receptors

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