A cell-permeable

PD 168393 – 5 mg

Brand:
Cayman
CAS:
194423-15-9
Storage:
-20
UN-No:
Non-Hazardous - /

PD 168393 is a cell-permeable, irreversible inhibitor of EGFR kinase activity (IC50 = 0.70 nM).{23693} It is effective in vivo, suppressing the growth of human epidermoid carcinoma xenografts in mice.{23693} PD 168393 is used in cells and in vivo to irreversibly inhibit EGFR signaling.{32865,32866,32867}  

 

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Description

A cell-permeable, irreversible inhibitor of EGFR kinase activity (IC50 = 0.70 nM); used in cells and in vivo to irreversibly inhibit EGFR signaling

Formal name: N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-propenamide

Synonyms: 

Molecular weight: 369.2

CAS: 194423-15-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|EGFR/ErbB/HER Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling

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