A nonpeptidic HIV aspartyl protease inhibitor (Ki = < 1 nM)

Tipranavir – 1 mg

Brand:
Cayman
CAS:
174484-41-4
Storage:
-20
UN-No:
Non-Hazardous - /

Tipranavir is a potent, orally bioavailable nonpeptidic HIV aspartyl protease inhibitor (Ki = < 1 nM) that prevents cleavage and thus activation of functional HIV cleaved proteins.{34181,34180} Formulations containing tipranavir, in combination with other HIV treatments, are effective against multidrug resistant viruses and are used in the treatment of HIV infection progression in patients who have not responded well to initial treatments.{34179}  

 

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Description

A nonpeptidic HIV aspartyl protease inhibitor (Ki = < 1 nM)

Formal name: N-[3-[(1R)-1-[(6R)-5,6-dihydro-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-2H-pyran-3-yl]propyl]phenyl]-5-(trifluoromethyl)-2-pyridinesulfonamide

Synonyms:  PNU-140690

Molecular weight: 602.7

CAS: 174484-41-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals|Protease Inhibitors||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS

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