Description
A positive allosteric modulator of the α7-containing nAChRs, increasing the peak amplitude of the current flowing through α7-containing nAChRs when applied with ACh (EC50 = 3.4 µM); modestly brain-penetrant and counteracts (-)-scopolamine-induced deficit in acquisition of a water-maze learning task in rats
Formal name: N-(5-chloro-2-hydroxyphenyl)-N’-[2-chloro-5-(trifluoromethyl)phenyl]-urea
Synonyms: NSC 213859
Molecular weight: 365.1
CAS: 501684-93-1
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Ion Channel Modulation|Activators||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory