A µ-opioid receptor agonist that does not induce arrestin-mediated receptor internalization

Herkinorin – 1 mg

Brand:
Cayman
CAS:
862073-77-6
Storage:
-20
UN-No:
Non-Hazardous - /

Herkinorin (Item No. 20925) is an analytical reference standard that is functionally categorized as an opioid. It is a natural neoclerodane diterpene from S. divinorum that preferentially activates the µ-opioid receptor.{34410,34411} Unlike the peptide DAMGO (Item No. 21553), herkinorin activates µ-opioid receptors without inducing arrestin-mediated receptor internalization.{34410,34414} Herkinorin has antinociceptive effects in rats.{34412} It has been identified as a novel psychoactive substance in multiple agitated emergency department patients screened in a non-targeted manner.{34413} This product is intended for research and forensic applications.  

 

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Description

A µ-opioid receptor agonist that does not induce arrestin-mediated receptor internalization

Formal name: (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid, methyl ester

Synonyms: 

Molecular weight: 494.5

CAS: 862073-77-6

Purity: ≥98%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Research Area|Forensic Chemistry & Toxicology|Opioids

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