A SERM that evokes tissue-dependent effects similar to that of tamoxifen

Toremifene (citrate) – 500 mg

Brand:
Cayman
CAS:
89778-27-8
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Toremifene (citrate) is an orally bioavailable selective estrogen receptor modulator (SERM) that evokes tissue-dependent effects similar to that of tamoxifen (Item No. 13258).{23588} It has been shown to block estrogen-stimulated growth of MCF-7 breast cancer cells grown in tissue culture, to inhibit ovariectomy-induced bone loss in rats, and to stimulate endometrial growth similar to that of tamoxifen.{23588}  

 

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Description

A SERM that evokes tissue-dependent effects similar to that of tamoxifen

Formal name: 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine, 2-hydroxy-1,2,3-monopropanetricarboxylate

Synonyms:  GTx-006|NK 622|NSC 613680

Molecular weight: 598.1

CAS: 89778-27-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology||Research Area|Cancer||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology

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