An atypical antipsychotic drug that displays high affinity for histamine (H)

Loxapine (succinate) – 100 mg

Brand:
Cayman
CAS:
27833-64-3
Storage:
-20
UN-No:
Non-Hazardous - /

Loxapine is an atypical antipsychotic drug that displays high affinity for histamine, 5-HT, dopamine, and α1-adrenergic receptors (Ki values are 7, 7.7, 9.5, 12, and 31 nM for H1, 5-HT2A, 5-HT2C, D2, and α1A, respectively).{24252,24253} It reduces agitation associated with schizophrenia or bipolar disorder.{32724}  

 

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SKU: 20760 - Category:

Description

An atypical antipsychotic drug that displays high affinity for histamine (H), serotonin (5-HT), dopamine (D), and α1-adrenergic receptors (Ki values are 7, 7.7, 9.5, 12, and 31 nM for H1, 5-HT2A, 5-HT2C, D2, and α1A, respectively)

Formal name: 2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine succinate

Synonyms:  CL 71,563

Molecular weight: 445.9

CAS: 27833-64-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology||Research Area|Neuroscience|Behavioral Neuroscience|Bipolar Disorder||Research Area|Neuroscience|Behavioral Neuroscience|Schizophrenia & Psychosis

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