A synthetic corticosteroid that potently activates the glucocorticoid receptor (Kd = 0.5 nM); investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to airway diseases

Fluticasone Propionate – 5 mg

Brand:
Cayman
CAS:
80474-14-2
Storage:
-20
UN-No:
Non-Hazardous - /

Fluticasone propionate is a synthetic corticosteroid that potently activates the glucocorticoid receptor (Kd = 0.5 nM).{33206} It has low systemic bioavailability and has been investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to asthma, allergic rhinitis, and other airway diseases.{33157,32981,33205}  

 

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Description

A synthetic corticosteroid that potently activates the glucocorticoid receptor (Kd = 0.5 nM); investigated for effectiveness as an inhaled or intranasal corticosteroid to reduce airflow obstruction related to airway diseases

Formal name: (6α,11β,16α,17α)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid, S-(fluoromethyl) ester

Synonyms:  Fluticasone 17-Propionate

Molecular weight: 500.6

CAS: 80474-14-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Glucocorticoids & Mineralocorticoids||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma

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