An ultra-LABA that has 1

Vilanterol – 5 mg

Brand:
Cayman
CAS:
503068-34-6
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Vilanterol is an ultra-long acting β2-adrenoceptor agonist (ultra-LABA) that has 1,000-fold selectivity for β2 over other β-receptors (pEC50s = 6.4, 9.4, and 6.1 for β1, β2, and β3, respectively).{32607,36208} In addition to its potency and selectivity, vilanterol is characterized by rapid onset of activity and prolonged duration of action.{32607,32608} It is being evaluated in clinical trials for airway disorders, including chronic obstructive pulmonary disease. Vilanterol is most effective in respiratory disorders when combined with inhaled corticosteroids or long-acting muscarinic antagonists.{29503,32133}  

 

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Description

An ultra-LABA that has 1,000-fold selectivity for β2-adrenoceptor over other β-receptors (pEC50s = 6.4, 9.4, and 6.1 for β1, β2, and β3, respectively)

Formal name: α1R-[[[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexyl]amino]methyl]-4-hydroxy-1,3-benzenedimethanol

Synonyms:  GW 642444

Molecular weight: 486.4

CAS: 503068-34-6

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation|Pulmonary Diseases|COPD/Emphysema

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