A cyclic depsipeptide antibiotic that is active against Gram-positive bacteria in vitro and leukemia P388 tumors in mice; acts as a bifunctional DNA intercalator that strongly binds DNA and forms crosslinks between DNA molecules

Sandramycin – 1 mg

Brand:
Cayman
CAS:
100940-65-6
Storage:
-20
UN-No:
Non-Hazardous - /

Sandramycin is a cyclic depsipeptide antibiotic that was first isolated from the culture broth of Nocardioides sp.{32105} It is active against Gram-positive bacteria in vitro and leukemia P388 tumors in mice.{32105} Sandramycin acts as a bifunctional DNA intercalator that strongly binds DNA and forms crosslinks between DNA molecules.{32104}  

 

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SKU: 20575 - Category:

Description

A cyclic depsipeptide antibiotic that is active against Gram-positive bacteria in vitro and leukemia P388 tumors in mice; acts as a bifunctional DNA intercalator that strongly binds DNA and forms crosslinks between DNA molecules

Formal name: N-[(3-hydroxy-2-quinolinyl)carbonyl]-D-seryl-(2S)-2-piperidinecarbonylglycyl-N-methylglycyl-N-methyl-L-valine, bimol. (5→1’3),(5’→13)-dilactone

Synonyms:  (-)-Sandramycin

Molecular weight: 1,221.30

CAS: 100940-65-6

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Polypeptides||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Peptides||Research Area|Cancer|DNA Damage and Repair|DNA Intercalating Agents||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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