LTF4 is a cysteinyl-leukotriene produced in vitro

Leukotriene F4 – 50 µg

Brand:
Cayman
CAS:
83851-42-7
Storage:
-80
UN-No:
De Minimis - 1230 / 3

LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle.{547} The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4.{547,548}  

 

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Description

LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle.{547} The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4.{547,548}

Formal name: 5S-hydroxy-6R-(S-γ-glutamylcysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid

Synonyms:  LTF4

Molecular weight: 568.7

CAS: 83851-42-7

Purity: ≥97%

Formulation: A solution in methanol

Product Type|Biochemicals|Lipids|Leukotrienes||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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