A nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry; can be detected using a fluorescent azide probe and copper catalysis using 1

5-Ethynyl-2′-deoxyuridine – 100 mg

Brand:
Cayman
CAS:
61135-33-9
Storage:
-20
UN-No:
Non-Hazardous - /

5-Ethynyl-2′-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.{32475,32476} Like 5-bromo-2’-deoxyuridine (BrdU; Item No. 15580), EdU is incorporated into DNA during active DNA synthesis. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition.{32476} Modified nucleosides, including EdU, can be cytotoxic when added to cells for prolonged periods.{32477}  

 

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Description

A nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry; can be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition

Formal name: 2′-deoxy-5-ethynyl-uridine

Synonyms:  2′-deoxy-5-Ethynyluridine|5-EdU|EdU

Molecular weight: 252.2

CAS: 61135-33-9

Purity: ≥98%

Formulation: A crystalline solid

Application|Click Chemistry||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Research Area|Cell Biology|Cell Cycle||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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