A synthetic progestin; has no estrogenic

Dydrogesterone – 10 mg

Brand:
Cayman
CAS:
152-62-5
Storage:
-20
UN-No:
Non-Hazardous - /

Dydrogesterone is a synthetic progestogen that has no estrogenic, androgenic, glucocorticoid, or anabolic effects, although it is an agonist of progesterone receptors (EC50 = 12.3 nM) and an antagonist of androgen, mineralocorticoid, and glucocorticoid receptors (IC50s = 28.6, 82.7, and 363 nM, respectively).{46018,46019} Dydrogesterone protects against sound stress-induced abortion in mice when administered at a dose of 1.25 mg per animal prior to the stressor on day five of pregnancy.{46020} Formulations containing dydrogesterone have been used in hormone replacement therapy, in the treatment of menstrual disorders, and to prevent miscarriage.  

 

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Description

A synthetic progestin; has no estrogenic, androgenic, glucocorticoid, or anabolic effects; an agonist of progesterone receptors (EC50 = 12.3 nM); an antagonist of androgen, mineralocorticoid, and glucocorticoid receptors (IC50s = 28.6, 82.7, and 363 nM, respectively); protects against sound stress-induced abortion in mice at 1.25 mg per animal on day five of pregnancy

Formal name: (9β,10α)-pregna-4,6-diene-3,20-dione

Synonyms:  NSC 92336

Molecular weight: 312.5

CAS: 152-62-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Androgens||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Glucocorticoids & Mineralocorticoids||Research Area|Endocrinology & Metabolism|Reproductive Biology

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