A mycotoxin; cytotoxic to primary rat hepatocytes at 125

Fumonisin B3 – 1 mg

Brand:
Cayman
CAS:
1422359-85-0
Storage:
-20
UN-No:
- 2811 / 6.1

Fumonisin B3 (FB3) is a mycotoxin that has been found in Fusarium.{61108} It is cytotoxic to primary rat hepatocytes when used at concentrations of 125, 250, and 500 µM.{61109} Dietary administration of FB3 (0.05%) for 14 or 21 days induces hepatocyte nodules, a marker of cancer initiation, in rats. FB3 has been detected in corn and corn-based foods and livestock feeds.{61110}  

 

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Description

A mycotoxin; cytotoxic to primary rat hepatocytes at 125, 250, and 500 µM; induces hepatocyte nodules in rats at 0.05% in the diet for 14 or 21 days; has been detected in corn and corn-based foods and livestock feeds

Formal name: (2R,2’R)-1,1′-[(1S,2R)-1-[(2S,4R,11S,12S)-12-amino-4,11-dihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl]ester, 1,2,3-propanetricarboxylic acid

Synonyms:  FB3

Molecular weight: 705.8

CAS: 1422359-85-0

Purity: ≥98%

Formulation: A powder

Product Type|Biochemicals|Toxins|Mycotoxins||Research Area|Cancer||Research Area|Toxicology|Cell Health & Viability

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