An inhibitor of cardiac late INa channels (IC50 = 3.4 µM) and IKr channels (IC50 = 1.5 µM); used clinically to suppress arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure

Flecainide (acetate) – 25 mg

Brand:
Cayman
CAS:
54143-56-5
Storage:
-20
UN-No:
Non-Hazardous - /

Flecainide is an inhibitor of cardiac late sodium current (INa; IC50 = 3.4 µM) and delayed-rectifier potassium current (IKr; IC50 = 1.5 µM).{32107,30900,29898} Formulations containing flecainide have been used in the treatment of arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure.  

 

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Description

An inhibitor of cardiac late INa channels (IC50 = 3.4 µM) and IKr channels (IC50 = 1.5 µM); used clinically to suppress arrhythmias and sodium-dependent calcium overload associated with myocardial ischemia and heart failure

Formal name: N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-benzamide, monoacetate

Synonyms: 

Molecular weight: 474.4

CAS: 54143-56-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Research Area|Cardiovascular System|Cardiovascular Diseases|Heart Failure||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Cardiovascular System|Heart|Arrhythmia

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