A fluoroquinolone antibiotic; active stereoisomer of ofloxacin; active against S. aureus

Levofloxacin – 1 g

Brand:
Cayman
CAS:
100986-85-4
Storage:
-20
UN-No:
Non-Hazardous - /

Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin (Item No. 22891).{42719} It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 μg/ml, respectively).{45220} Levofloxacin inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s = 8.06 and 9.81 μg/ml, respectively).{27493} It eliminates infection in rat models of endocarditis caused by methicillin-sensitive or -resistant S. aureus.{42992} Formulations containing levofloxacin have been used in the treatment of various bacterial infections.  

 

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SKU: 20382 - Category:

Description

A fluoroquinolone antibiotic; active stereoisomer of ofloxacin; active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 μg/ml, respectively); inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s = 8.06 and 9.81 μg/ml, respectively); eliminates infection in rat models of endocarditis caused by methicillin-sensitive or -resistant S. aureus

Formal name: (3S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid

Synonyms:  MP-376

Molecular weight: 361.4

CAS: 100986-85-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Quinolones & Fluoroquinolones||Product Type|Biochemicals|Small Molecule Inhibitors|Nucleic Acid Turnover/Signaling||Product Type|Biochemicals|Small Molecule Inhibitors|Topoisomerases||Research Area|Cardiovascular System|Heart||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia

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