A natural oxidant that can generate O2- in alkaline solutions through autoxidation to a semiquinone radical

Pyrogallol – 50 g

Brand:
Cayman
CAS:
87-66-1
Storage:
-20
UN-No:
Limited Quantity - 2811 / 6.1

Pyrogallol is a natural oxidant that can generate superoxide (O2-) in alkaline solutions through autoxidation to a semiquinone radical.{32348} Importantly, the semiquinone radical can react with O2- in an acidic environment to produce a quinone and H2O2.{32348} Pyrogallol autoxidation is used in superoxide dismutase activity assays.{32348} It can also be used in assays to assess antioxidant capacity.{32347,25176} Pyrogallol is used in some biological systems as an O2- scavenger.{32352} In other biological systems, it is used as an O2- generator.{32351,10231} Pyrogallol effectively scavenges DPPH radical (Item No. 14805) and ABTS+ in vitro.{32349} Pyrogallol is a product of tannin degradation to gallic acid (Item No. 11846) by ruminant microbes and has hepatotoxic and nephrotoxic effects in vivo.{32350}  

 

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Description

A natural oxidant that can generate O2- in alkaline solutions through autoxidation to a semiquinone radical, which in turn can react with O2- in an acidic environment to produce a quinone and H2O2; used in superoxide dismutase and antioxidant assays, as well as in biological systems

Formal name: 1,2,3-benzenetriol

Synonyms:  1,2,3-Trihydroxybenzene|2,3-dihydroxy Phenol|Antioxidant PY|Benzene-1,2,3-triol|C.I. 76515|Fouramine Brown AP|NSC 5035

Molecular weight: 126.1

CAS: 87-66-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Ox Stress Reagents|Free Radical Generators||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Pro-oxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase

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