A mycobacterial ATP synthase inhibitor that demonstrates potent activity against both drug-sensitive and drug-resistant M. tuberculosis with MIC50 values of ~0.03 µg/ml

TMC207 – 5 mg

Brand:
Cayman
CAS:
843663-66-1
Storage:
-20
UN-No:
Non-Hazardous - /

TMC207 is a diarylquinoline that selectively inhibits the proton pump of the mycobacterial ATP synthase.{31976} It demonstrates potent activity against both drug-sensitive and drug-resistant M. tuberculosis and other mycobacterial species with MIC50 values of ~0.03 µg/ml.{31976}  

 

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SKU: 20247 - Category:

Description

A mycobacterial ATP synthase inhibitor that demonstrates potent activity against both drug-sensitive and drug-resistant M. tuberculosis with MIC50 values of ~0.03 µg/ml

Formal name: (αS,βR)-6-bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol

Synonyms:  Bedaquiline|R207910

Molecular weight: 555.5

CAS: 843663-66-1

Purity: ≥97%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Small Molecule Inhibitors|Oxidative Phosphorylation||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis

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