A partial agonist of CB2 receptors (EC50 = 0.65 nM); demonstrates anti-inflammatory and antihyperalgesic properties in animal models of inflammation and pain

GW 405833 – 25 mg

Brand:
Cayman
CAS:
180002-83-9
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

GW 405833 is a partial agonist of the cannabinoid CB2 receptor (EC50 = 0.65 nM).{16338} It is selective for CB2, binding with a Ki value of 14 nM compared to that of CB1 with a Ki value of 2.04 µM.{16338} GW 405833 demonstrates anti-inflammatory and antihyperalgesic properties in animal models of inflammation and pain.{16338}  

 

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Description

A partial agonist of CB2 receptors (EC50 = 0.65 nM); demonstrates anti-inflammatory and antihyperalgesic properties in animal models of inflammation and pain

Formal name: (2,3-dichlorophenyl)[5-methoxy-2-methyl-3-[2-(4-morpholinyl)ethyl]-1H-indol-1-yl]-methanone

Synonyms:  L-768,242

Molecular weight: 447.4

CAS: 180002-83-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Pain Research

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