A minor metabolite of the oligomycin complex that is active against Gram-positive bacteria and demonstrates strong antitumor activity against HeLa cells (IC50 = 14 ng/ml)

Oligomycin E – 5 mg

Brand:
Cayman
CAS:
110231-34-0
Storage:
-20
UN-No:
Non-Hazardous - /

Oligomycin E is a minor metabolite of the oligomycin complex (Item No. 11341) produced by several species of Streptomyces. It exhibits relatively weak antifungal activity compared to other oligomycins, yet is active against Gram-positive bacteria and demonstrates strong antitumor activity against HeLa cells (IC50 = 14 ng/ml).{31740}  

 

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SKU: 20185 - Category:

Description

A minor metabolite of the oligomycin complex that is active against Gram-positive bacteria and demonstrates strong antitumor activity against HeLa cells (IC50 = 14 ng/ml)

Formal name: (1R,2’S,4E,5’S,6S,6’S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28R,29R)-22-ethyl-5′,6′-dihydro-7,11,14,15,28-pentahydroxy-6′-[(2R)-2-hydroxypropyl]-5′,6,8,10,12,14,16,28,29-nonamethyl-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2′-[2H]pyran]-3,3′,9,13(4’H)-tetrone

Synonyms:  26-hydroxy-28-oxo-Oligomycin A

Molecular weight: 821.1

CAS: 110231-34-0

Purity: ≥95%

Formulation: A lyophilisate

Product Type|Biochemicals|Antibiotics|Macrolides||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases

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