A cytotoxic Streptomyces metabolite that inhibits topoisomerase II and hepatitis C viral replication

UK 1 – 5 mg

Brand:
Cayman
CAS:
151271-53-3
Storage:
-20
UN-No:
Non-Hazardous - /

UK 1 is a metabolite from Streptomyces sp. 517-02 that demonstrates cytotoxic activity against various cancer cell lines, though it does not have antibacterial effects.{31697} It has been shown to inhibit topoisomerase II and also to inhibit hepatitis C viral replication.{31696,31698}  

 

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Description

A cytotoxic Streptomyces metabolite that inhibits topoisomerase II and hepatitis C viral replication

Formal name: 2′-(2-hydroxyphenyl)-[2,4′-bibenzoxazole]-4-carboxylic acid, methyl ester

Synonyms: 

Molecular weight: 386.4

CAS: 151271-53-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Topoisomerases||Research Area|Cancer|DNA Damage and Repair|Topoisomerase||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Hepatitis

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