A tetracyclic lantibiotic that demonstrates antiviral activity against HSV-1; also used as a probe for analyzing the transbilayer movement of phosphatidylethanolamine

Cinnamycin – 5 mg

Brand:
Cayman
CAS:
110655-58-8
Storage:
-20
UN-No:
Non-Hazardous - /

Cinnamycin is tetracyclic lantibiotic produced from S. cinnamoneus that contains four unusual amino acids: erythro-β-hydroxyaspartic acid, mesolanthionine, threo-β-methyllanthionine, and lysinoalanine.{31695} Cinnamycin has demonstrated antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells via a cytopathic effect reduction assay.{31695} Cinnamycin recognizes the structure of phosphatidylethanolamine and forms an equimolar complex with the phospholipid on biological membranes.{27114} This peptide has been used as a probe for analyzing the transbilayer movement of phosphatidylethanolamine.{31694}  

 

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Description

A tetracyclic lantibiotic that demonstrates antiviral activity against HSV-1; also used as a probe for analyzing the transbilayer movement of phosphatidylethanolamine

Formal name: L-cysteinyl-L-arginyl-L-glutaminyl-D-cysteinyl-L-cysteinyl-3-aminoalanyl-L-phenylalanylglycyl-L-prolyl-L-phenylalanyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-phenylalanyl-L-valyl-L-cysteinyl-(3R)-3-hydroxy-L-a-aspartylglycyl-L-asparaginyl-(2S,3S)-2-amino-3-mercaptobutanoyl-L-lysine,cyclic (1→18)​,​(4→14)​,​(5→11)​-​tris(thioether),cyclic (6→19)​-​imine

Synonyms:  Lanthiopeptin|NSC 71936|Ro 09-0198

Molecular weight: 2,041.30

CAS: 110655-58-8

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Peptides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HSV

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