A fluorescent probe for cell membrane electrical activity using FRET; ex/em = 540/560 nm

DISBAC10 – 5 mg

Brand:
Cayman
CAS:
169211-45-4
Storage:
-20
UN-No:
De Minimis - 1231 / 3

DISBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity using FRET.{2601} DISBAC10 displays excitation/emission spectra of 540/560 nm, respectively. In a resting polarized cell, DISBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength.{2601} Depolarization of the cell causes rapid translocation of DISBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal. DISBAC10 can also be used in conjunction with fluorescein-labeled antibodies or receptor ligands to visualize specific cell classes.  

 

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SKU: 200280 - Category:

Description

A fluorescent probe for cell membrane electrical activity using FRET; ex/em = 540/560 nm, respectively; can be used in conjunction with fluorescein-labeled antibodies or receptor ligands to visualize specific cell classes,

Formal name: 1,3-didecyl-5-[3-(1,3-didecylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione

Synonyms: 

Molecular weight: 885.4

CAS: 169211-45-4

Purity: ≥98%

Formulation: A solution in methyl acetate

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area

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