An activator of voltage-sensitive L-type calcium channels; vasoconstrictive and positive inotropic effects in vivo

(S)-(−)-BAY-K-8644 – 5 mg

Brand:
Cayman
CAS:
98625-26-4
Storage:
-20
UN-No:
Non-Hazardous - /

(S)-(−)-BAY-K-8644 is an activator of voltage-sensitive L-type calcium channels.{24673,24676} It demonstrates vasoconstrictive and positive inotropic effects in vivo as well as behavioral effects, including deficits to motor function.{24675,24674} When combined with BIX01294 (Item No. 13124), (S)-(−)-BAY-K-8644 can enable reprogramming of mouse embryonic fibroblasts after transduction with Oct4/Klf4.{17549}  

 

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Description

An activator of voltage-sensitive L-type calcium channels; vasoconstrictive and positive inotropic effects in vivo

Formal name: (4S)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester

Synonyms: 

Molecular weight: 356.3

CAS: 98625-26-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Activators||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Cell Biology|Stem Cell Research|Reprogramming||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Neuroscience|Behavioral Neuroscience

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