An inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM

MRT68921 – 5 mg

Brand:
Cayman
CAS:
1190379-70-4
Storage:
-20
UN-No:
Non-Hazardous - /

MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively).{32504} Through its effects on ULK1, MRT68921 blocks autophagy in cells, driving the accumulation of stalled early autophagosomal structures.{32504}  

 

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SKU: 19905 - Category:

Description

An inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively); blocks autophagy in cells

Formal name: N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxamide

Synonyms: 

Molecular weight: 434.6

CAS: 1190379-70-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|Other Serine/Threonine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy

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