A mitochondrial antioxidant; decreases transmembrane potential and production of ROS; prevents neuronal loss and synaptic damage in rat AD model; slows development of ocular pathologies; prevents acute phenoptosis following rhabdomyolysis

SKQ1 (bromide) – 5 mg

Brand:
Cayman
CAS:
934826-68-3
Storage:
-20
UN-No:
De Minimis - 1170 / 3

SKQ1 (bromide) is a mitochondria-targeted antioxidant that decreases transmembrane potential and production of reactive oxygen species (ROS).{34427} SKQ1 prevents neuronal loss and synaptic damage in a rat model of spontaneous Alzheimer’s disease, as well as decreases severity of arthritic lesions in rats.{34430,34431} SKQ1 slows development of age-related ocular pathologies in murine, porcine, bovine, and canine model systems.{34429} It also prevents acute phenoptosis following rhabdomyolysis, stroke, and myocardial infarction.{34426,34428,34432}  

 

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Description

A mitochondrial antioxidant; decreases transmembrane potential and production of ROS; prevents neuronal loss and synaptic damage in rat AD model; slows development of ocular pathologies; prevents acute phenoptosis following rhabdomyolysis, stroke, and myocardial infarction

Formal name: [10-(4,5-dimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl]triphenyl-phosphonium, monobromide

Synonyms: 

Molecular weight: 617.6

CAS: 934826-68-3

Purity: ≥95%

Formulation: A solution in ethanol and water (1:1)

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Cardiovascular System|Cardiovascular Diseases|Stroke||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease||Research Area|Neuroscience|Ophthalmology

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