Rutin (hydrate) – 100 g

Brand:
Cayman
CAS:
250249-75-3
Storage:
22
UN-No:
Non-Hazardous - /

Rutin is a flavonoid glycoside that has been found in buckwheat and has diverse biological activities.{30137,31793,16519,31794,31795} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals when used at a concentration of 163.79 µM, as well as inhibits iron autoxidation, in cell-free assays.{30137,31793} Dietary administration of rutin (0.2% w/v) reduces tumor growth and the number of lung metastases in a B16/F10 murine melanoma model.{16519} Rutin (50 and 100 mg/kg) decreases intestinal acidity, increases intestinal activity of superoxide dismutase (SOD) and catalase, and reduces intestinal levels of protein carbonyls and thiobarbituric acid reactive substances (TBARS) formation in a rat model of intestinal toxicity induced by methotrexate (Item No. 13960).{31794} It also increases the time spent exploring the novel object in the novel object recognition (NOR) test and increases recognition and discriminative indices in a rat model of short-term episodic memory deficits induced by scopolamine (Item No. 14108).{31795}  

 

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SKU: 19868 - Category:

Description

A flavonoid glycoside with diverse biological activities; scavenges DPPH and ABTS radicals at 163.79 µM, as well as inhibits iron autoxidation, in cell-free assays; dietary administration reduces tumor growth and the number of lung metastases in a B16/F10 murine melanoma model at 0.2% w/v; decreases intestinal acidity, increases intestinal activity of SOD and catalase, and reduces intestinal levels of protein carbonyls and TBARS formation in a rat model of methotrexate-induced intestinal toxicity at 50 and 100 mg/kg; increases the time spent exploring the novel object in the NOR test and increases recognition and discriminative indices in a rat model of scopolamine-induced short-term episodic memory deficits


Formal name: 3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, trihydrate

Synonyms:  Quercetin-3-O-rutinoside|Rutoside|Sophorin

Molecular weight: 664.6

CAS: 250249-75-3

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Protein Oxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Catalase||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase