Description
A phenol with diverse biological activities; inhibits LPS- and IFN-γ-induced migration and production of ROS in BV-2 microglia at 10 and 30 µM; inhibits compound 48/80-induced histamine release from rat peritoneal mast cells; reduces mortality in a mouse model of compound 48/80-induced anaphylactic shock at 0.5 mg/animal; reduces hepatic necrosis and serum levels of ALT and AST in a mouse model of acetaminophen-induced hepatotoxicity at 100 mg/kg; inhibits carrageenan-induced thermal hyperalgesia and production of NO and PGE2 in rats at 30, 50, and 100 mg/kg
Formal name: 1-(2-hydroxy-4-methoxyphenyl)-ethanone
Synonyms: 2′-Hydroxy-4′-methoxyacetophenone|NSC 401442
Molecular weight: 166.2
CAS: 552-41-0
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cell Biology|Cell Death|Necrosis||Research Area|Cell Biology|Cell Signaling|Nitric Oxide Signaling||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity|Sepsis/Shock||Research Area|Neuroscience|Pain Research||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen
